China Medical System: Self-developed Innovative Drug Complement Factor B Inhibitor CMS-D017 is Approved for Drug Clinical Trials for Age-related Macular Degeneration

CMS-D017 is a novel selective small-molecule inhibitor of complement factor B (CFB). Through administered orally, targeting and inhibiting complement factor B,it blocks abnormal activation of the alternative complement pathway, and thereby slows the progression of complement dysregulation-related diseases such as age-related macular degeneration (“AMD”), offering a potentially superior and more convenient treatment option[1]. CMS-D017 has demonstrated favourable efficacy and safety profiles in preclinical studies. Upon approval for marketing, CMS-D017 will synergise with the marketed innovative drug Beovu®(diabetic macular oedema, etc.), the branded drug Lucentis® (neovascular age-related macular degeneration, etc.), and the exclusive drug Augentropfen Stulln Mono Eye Drops (senile macular degeneration and all forms of asthenopia), building a multi-layered, precise and comprehensive solution for ophthalmic diseases.   China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that on 15 July 2026, the Group’s self-developed innovative drug, Complement Factor B inhibitor CMS-D017 capsules (“CMS-D017” or the “Product”), obtained the Drug Clinical Trial Approval Notice […]