CMS: Class 1 Innovative Drug Silevimig Injection Approved in China, Becoming the World’s First Bispecific Antibody for Passive Immunization Against Rabies

Silevimig Injection is the world’s first fully human bispecific antibody targeting dual epitopes of the rabies virus, which is consistent with the WHO recommendation for a “cocktail” therapeutic paradigm; Silevimig Injection provides immediate protection, can be manufactured at scale with standardized processes, and carries no risks of blood-borne infections. Silevimig Injection is the passive immunization product with the smallest dose for rabies, resulting in less injection volume and easier administration, which can effectively reduce patient pain and improve compliance. Silevimig Injection will provide patients with a new option for passive immunization against rabies, and efficiently synergize with the Group’s existing expert network and market resources.   China Medical System Holdings Limited (“CMS”, or the “Group”) is pleased to announce that, the New Drug Application for Silevimig Injection (GR1801, the “Product”, trade name: 金速希®), a Class 1 therapeutic biological product has been approved by the National Medical Products Administration of the […]

2026 ADA | CMS’s Self-developed Innovative INHBE-Targeting siRNA Drug CMS-D008 Presents Its Preclinical Results

China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that the preclinical results of its self-developed innovative INHBE-targeting small nucleic acid drug CMS-D008 injection (“CMS-D008”), have been presented in a poster at the American Diabetes Association (ADA) 86th Scientific Sessions (June 5-8, 2026, New Orleans, USA). As the world’s largest and most authoritative annual scientific meeting in the fields of diabetes and metabolic diseases, it convened over 12,000 leading clinicians, researchers, and healthcare professionals worldwide to explore cutting-edge advances in diagnostics, therapies, and technologies.   About CMS-D008 CMS-D008 is a self-developed novel siRNA therapy administered by subcutaneous injection. It targets and reduces the hepatic expression of the inhibin subunit beta E (INHBE) gene and lowers the level of INHBE-encoded Activin E protein, which blocks Activin E-ALK7 signaling and reduces fat accumulation effectively. It demonstrates the potential for high-quality, long-term weight loss that boosts fat-specific loss while preserving muscle mass. Currently, the […]

CMS Charity | Love Like Starlight: CMS Continues to Care for Children’s Growth

Growing toward the light, together in warmth. With International Children’s Day approaching, China Medical System Holdings Limited (“CMS”), through its subsidiary Shenzhen Kangzhe, continued its long-standing philanthropic initiatives. Via the Charity Association of Shenzhen Nanshan, CMS donated funds to the Star Exceptional Children Rehabilitation Center in Nanshan District, Shenzhen. The donation will be used to upgrade teaching aids, add rehabilitation equipment, and provide support for frontline teachers—helping improve learning, rehabilitation, and living conditions for exceptional children. Over the years, CMS has stood side-by-side with the Center, witnessing every small step of progress in the rehabilitation and growth of these children. This enduring commitment stems from a deep compassion for special-needs children and a profound understanding of philanthropic values: their development demands patience, sustained support, and collective care from society. In addition, CMS donated 10 computers to the Green & Shine Foundation to help improve educational facilities in schools across central and western China, supporting daily teaching […]

CMS Wins Dual Honors at the 2026 “Golden Kunpeng”: “Best Listed Company” and “Most Investable Listed Company”

On 26 May 2026, the 2026 Global Commercial Newspaper Economic Forum and the “Golden Kunpeng” China Financial Value Ranking Awards Ceremony, co-hosted by the Global Commercial Newspaper Alliance and Hong Kong Commercial Daily, was held in Hong Kong. China Medical System Holdings Limited (“CMS” or the “Group”) stood out among a broad field of participating companies on the strength of its solid fundamentals and sustainable growth outlook, winning two awards: “Best Listed Company” and “Most Investable Listed Company”. Meanwhile, based on the Group’s overall performance in innovative R&D, growth and liquidity, the Group was officially included as a constituent of the Hong Kong Commercial Daily Technology Index.     The “Best Listed Company” award provides a comprehensive assessment across core indicators including financial performance, corporate governance, ESG practices and market influence, while the “Most Investable Listed Company” award focuses on dimensions such as the sustainability of the business model, financial soundness and industry growth potential. […]

China Medical System’s Innovative Drug Highly Selective TYK2 Inhibitor CMS-D001 is Approved for Drug Clinical Trials for Ulcerative Colitis and Crohn’s Disease

  CMS-D001 is an oral highly selective TYK2 inhibitor. It can reduce the impact on other JAK family kinases, and is expected to lower safety risks while maintaining efficacy.   Currently, no TYK2 inhibitor has been approved globally for the indications of ulcerative colitis and Crohn’s disease. CMS-D001 proactively positions in the gastroenterologytherapeutic area, and is expected to become an emerging oral therapy for ulcerative colitis and Crohn’s disease; it can synergise with the Group’s marketed products Salofalk and the exclusive product Bioflor, strengthening whole-cycle, whole-disease-course management of intestinal diseases, and enhancing the Group’s competitive position in the gastroenterology therapeutic area.   China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that, on 22 May 2026, the innovative drug highly selective TYK2 (tyrosine kinase 2) inhibitor CMS-D001 Tablets (“CMS-D001” or the “Product”) has been granted the Drug Clinical Trial Approval Notice by the National Medical Products Administration of the People’s Republic […]

CMS 34th Anniversary | Moving with Time, Growing for Tomorrow

Thirty-four years have been a journey of walking side by side, preserved in photographs, and a process of building solid foundations step by step for future breakthroughs. Every captured moment is etched with the mark of CMSer: pragmatic and hardworking, rising to challenges, and striving for breakthroughs and progress. These accumulated achievements are not only a testament we can look back on, but also the confidence and strength that enable CMS to navigate cycles and continue growing upward. Since 2018, CMS has initiated a transformation of growth momentum with innovation at its core, driving a systematic upgrade of its development model. The Group has remained guided by clinical needs, centered on product value, and supported by system capabilities. It has built differentiated innovation pipelines through multiple pathways and strengthened full-lifecycle management capabilities. CMS has enhanced commercialization efficiency through the collaboration between deep specialty focus and omni-channel marketing, and has promoted […]

CMS Signed An Exclusive Commercialization and Supply Agreement for Marketed Originator Intravenous Iron Products Monofer® and Cosmofer®

  Iron IsomaltosideInjection (Monofer®) is an exclusive drug and the first third-generation intravenous iron therapy approved for marketing in China, providing a better safety profile[1]. Its single-dose full iron replenishment significantly reduces the number of infusions, enables faster improvement in hemoglobin levels and enhances clinical convenience. Iron Dextran Injection (Cosmofer®)is currently the only intravenous iron therapy included in Category A of the NRDL and also the only one included in the NEML. With many years of accumulated clinical use, its efficacy and safety have been supported by accumulated clinical experience and published data. Two products will form a comprehensive intravenous iron product portfolio covering all channels and treatment scenarios, and will generateefficient synergies with the Group’s existing products across its key specialty areas, including gastroenterology, cardiology, nephrology, obstetrics and gynecology, and orthopedics.   China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that, the Group through its wholly-owned subsidiary entered into an exclusive […]

CMS: NDA for the Seasonal Allergic Rhinitis Indication of Class 1 Innovative Drug MG-K10 Accepted in China

MG-K10, a long-acting anti-IL-4Rα humanized monoclonal antibody injection, enables once-every-4-weeks dosing (whereas currently marketed drugs targeting the same pathway require dosing once every 2 weeks), which may improve treatment adherence. It is also expected to become the first long-acting anti-IL-4Rα monoclonal antibody to be marketed globally, demonstrating BIC potential. In a Phase III clinical trial in adult patients with moderate-to-severe SAR, MG-K10 has met the primary endpoint, demonstrating significantly superior efficacy compared with the placebo group, with a favorable safety profile. The acceptance of the NDA represents an important milestone for CMS Vision(the ophthalmology business) in expanding its therapeutic focus from ophthalmology into the field of ENT, and also marks another significant milestone in the Group’s R&D progress in the field of type 2 inflammatory diseases.     China Medical System Holdings Limited (the “Group” or “CMS”) is pleased to announce that the New Drug Application (NDA) in China for the Seasonal Allergic […]

CMS Included in S&P Global Sustainability Yearbook (China Edition) for the Fourth Consecutive Year

S&P Global, an internationally recognized rating agency, recently released the Sustainability Yearbook (China Edition) 2026. China Medical System (“CMS” or the “Group”) stood out among nearly 1,800 companies and was successfully included for the fourth consecutive year, underscoring the Group’s long-term resilience and comprehensive strengths in sustainable development. （Source：S&P Global）   CMS integrates the United Nations Sustainable Development Goals (“SDGs”) into the Group’s ESG strategy, guided by top-level planning, is driving a more sustainable transformation across the entire value chain. We are committed to improving accessibility and equity in healthcare, and continue to increase R&D investment in innovative medicines and treatments for rare diseases, addressing unmet clinical needs through scientific innovation. At the same time, we remain dedicated to inclusive healthcare, responding to societal needs through concrete actions and fulfilling the responsibilities expected of a pharmaceutical company. We also place strong emphasis on employee development and environmental protection, and steadily advance our responsible practices.   The Group’s […]

Performance Returns to Growth Trajectory丨CMS (867.HK, 8A8.SG) 2025 Annual Performance Report in One Picture

CMS: New Drug for Renal Anaemia Desidustat Tablets Approved in China

Desidustat Tablets are a noveloral HIF-PHI, approved for treating anaemia in non-dialysis adult CKD patients. The Product is administrated orally, thus expecting to improve the treatment compliance of patients and to meet the unmet treatment needs in the field of CKD anaemia. The China Phase III clinical trial of the Product has demonstrated positive results: the study met its primary efficacy endpoint. Extension study results demonstrated that the Product can maintain Hb level within the target range over the long term with acceptable safety, while significantly reducing hepcidin levels and ameliorating iron metabolism disorders. The Product will strengthen the Group’s layout in the field of nephrology and synergize with the marketed innovative drug Velphoro for CKD hyperphosphatemia in terms of expert resources and channel networks.   China Medical System Holdings Limited (“CMS”, or the “Group”) is pleased to announce that on 13 March 2026, new drug for renal anaemia Desidustat Tablets (the “Product”) has been […]

CMS : Ruxolitinib Phosphate Cream (Lumirix®) Achieves Initial Prescriptions in Multiple Regions in China for Patients with Vitiligo

On 12 March 2026, China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that its subsidiary, Dermavon Holdings Limited (“Dermavon”, an innovative pharmaceutical company specialized in skin health, which is applying for a separate listing on the Main Board of The Stock Exchange of Hong Kong Limited) has its innovative prescription medicine ruxolitinib phosphate cream (Lumirix®) (the “Product”, marketed as Opzelura® in the U.S., Europe and Canada) recorded the initial prescriptions for vitiligo patients across 30 provincial-level regions. The prescriptions cover approximately a thousand influential public and private medical institutions in the field of skin health and disease management, including Huashan Hospital, Fudan University, Shanghai Skin Disease Hospital, Dermatology Hospital of Southern Medical University, Second People’s Hospital of Chengdu, The First Bethune Hospital of Jilin University, The Second Xiangya Hospital of Central South University, United Family Healthcare Group, among others*. Meanwhile, the Product has become concurrently accessible via over 1,300 offline drugstores as well […]